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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D22B
All Species:
23.64
Human Site:
Y265
Identified Species:
47.27
UniProt:
Q9NU19
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NU19
NP_060242.2
505
59081
Y265
E
E
H
H
Q
D
T
Y
R
Q
I
H
I
D
I
Chimpanzee
Pan troglodytes
XP_527375
505
59106
Y265
E
E
H
H
Q
D
T
Y
R
Q
I
H
I
D
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_538894
488
57073
Q266
N
P
L
I
P
L
F
Q
Q
P
L
V
Q
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8R5A6
516
59344
Y276
D
E
V
H
Q
D
T
Y
R
Q
I
H
I
D
I
Rat
Rattus norvegicus
NP_001020230
505
59036
Y265
E
E
H
H
Q
D
T
Y
R
Q
I
H
I
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509397
560
64265
R267
Q
I
H
I
D
I
P
R
T
N
P
L
I
P
L
Chicken
Gallus gallus
XP_419261
747
85990
Y507
E
E
H
H
Q
D
T
Y
R
Q
I
H
I
D
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685523
523
60664
Y283
D
E
N
H
R
D
T
Y
R
Q
I
H
I
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650941
546
61493
T301
Q
D
E
T
Q
Q
D
T
Y
R
Q
I
H
I
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001023165
495
56525
F265
M
C
P
L
I
P
L
F
Q
Q
K
M
V
Q
E
Sea Urchin
Strong. purpuratus
XP_797601
498
57012
Q267
N
P
L
I
P
L
F
Q
E
P
V
V
Q
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08484
637
73271
H335
S
R
D
I
P
T
W
H
Q
I
E
I
D
I
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
95.4
N.A.
62.2
98.4
N.A.
79.6
63.3
N.A.
70.1
N.A.
43
N.A.
46.9
46.7
Protein Similarity:
100
100
N.A.
96
N.A.
76.7
99
N.A.
83.5
65.1
N.A.
81.6
N.A.
57.6
N.A.
62.1
65.5
P-Site Identity:
100
100
N.A.
6.6
N.A.
86.6
100
N.A.
13.3
100
N.A.
80
N.A.
6.6
N.A.
6.6
6.6
P-Site Similarity:
100
100
N.A.
26.6
N.A.
93.3
100
N.A.
26.6
100
N.A.
100
N.A.
26.6
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
9
9
0
9
50
9
0
0
0
0
0
9
50
9
% D
% Glu:
34
50
9
0
0
0
0
0
9
0
9
0
0
17
9
% E
% Phe:
0
0
0
0
0
0
17
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
42
50
0
0
0
9
0
0
0
50
9
0
0
% H
% Ile:
0
9
0
34
9
9
0
0
0
9
50
17
59
17
67
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% K
% Leu:
0
0
17
9
0
17
9
0
0
0
9
9
0
0
9
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
17
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
17
9
0
25
9
9
0
0
17
9
0
0
9
9
% P
% Gln:
17
0
0
0
50
9
0
17
25
59
9
0
17
9
0
% Q
% Arg:
0
9
0
0
9
0
0
9
50
9
0
0
0
0
0
% R
% Ser:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
9
0
9
50
9
9
0
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
0
0
0
0
9
17
9
0
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _